How is Hepatocarcinoma diagnosed?

How is Hepatocarcinoma diagnosed?

Diagnosis of HCC often requires more sophisticated imaging modalities such as CT scan and MRI, which have multiphasic contrast enhancement capabilities. Serum AFP used alone can be helpful if levels are markedly elevated, which occurs in fewer than half of cases at time of diagnosis.

Which is the most common serum tumor marker in hepatocellular carcinoma is?

Serum alpha fetoprotein (AFP) is the most widely used tumor marker in detecting patients with hepatocellular carcinoma, and has been proven to have capability of prefiguring the prognosis.

What means Hepatocarcinoma?

Liver cancer begins in the cells of the liver. The most common form of liver cancer begins in cells called hepatocytes and is called hepatocellular carcinoma. Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer.

Is hepatocellular carcinoma a fast growing cancer?

Liver cancer can spread quickly depending on the type of cancer. Hemangiosarcoma and angiosarcoma types of liver cancer are fast spreading, whereas hepatocellular carcinoma spreads late in the disease.

What are the tumor markers for HCC?

Alpha-fetoprotein (AFP), Lens culinaris agglutinin A-reactive fraction of alpha-fetoprotein (AFP-L3), and des-gamma-carboxy prothrombin (DCP) have been established as HCC-specific tumor markers [1,2,3,4,5,6,7,8,9,10,11,12,13,14].

What is the best treatment for hepatocellular carcinoma?

Orthotopic liver transplantation (OLT) is an effective treatment for both HCC and underlying cirrhosis, and is considered the best therapeutic option.

What is the BCLC staging system for hepatocellular carcinoma?

BCLC staging system. In brief, patients at stage 0 with very early HCC are optimal candidates for resection. Patients at stage A with early HCC are candidates for radical therapies (resection, liver transplantation or percutaneous treatments). Patients at stage B with intermediate HCC may benefit from chemoembolization.

How is hepatocellular carcinoma staged in Barcelona clinic liver cancer?

Barcelona clinic liver cancer (BCLC) staging uses a set of criteria to guide the management of patients with hepatocellular carcinoma (HCC). The classification takes the following variables into account 1,2: performance status (PS) Child-Pugh score. radiologic tumor extent.

What are the histologic findings of hepatocellular carcinoma 4 and 5?

Percentage of tumor necrosis for tumor 4 is 10%. Tumor 5 is located in the left lobe and 1.5 cm in size with no necrosis. Histologic type is hepatocellular carcinoma with grade G2 – G3: moderately to poorly differentiated. The tumor is confined to the liver and biliary and vascular margins are free of tumor.

What is the diagnostic marker for hepatocellular carcinoma (HCC)?

Borscheri N, Roessner A, Röcken C. Canalicular immunostaining of neprilysin (CD10) as a diagnostic marker for hepatocellular carcinomas. Am J Surg Pathol. 2001;25:1297–1303. [PubMed] [Google Scholar]